Epitope
Epitope Prediction
Task Overview
An epitope, also known as antigenic determinant, is the region of a pathogen that can be recognized by antibody and cause adaptive immune response. This task is to classify the active and non-active sites from the antigen protein sequences.
Impact
Identifying the potential epitope is of primary importance in many clinical and biotechnologies, such as vaccine design and antibody development, and for our general understanding of the immune system.
Generalization
The models are expected to be generalized to unseen pathogens antigens amino acid sequences with diverse set of structures and functions.
Product
Immunotherapy.
Pipeline Stage
Target discovery.
Available Datasets
Usage Example
You can access these datasets using the PyTDC library:
from tdc_ml.single_pred import Epitope
# Load a dataset
data = Epitope(name='IEDB_Jespersen')
# Access the data
df = data.get_data()
print(df.head())